Alpha gliadin antibody levels: a serological test for coeliac disease.
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چکیده
منابع مشابه
Alpha gliadin antibody levels: a serological test for coeliac disease.
The diagnostic value in coeliac disease of circulating antibodies to casein, crude gliadin, and alpha gliadin was assessed using an adaption of the enzyme linked immunosorbent assay system. alpha Gliadin was the only antigen which consistently separated 26 patients with untreated coeliac disease from 26 normal controls and 13 patients with chronic inflammatory bowel disease. The mean assay inde...
متن کاملHumoral response to alpha gliadin as serological screening test for coeliac disease.
The diagnostic value of measuring alpha gliadin antibodies in children with suspected coeliac disease has been evaluated prospectively. Jejunal biopsy and alpha gliadin antibody measurements were performed in 77 consecutive children who were being investigated for a suspected malabsorption syndrome. The typical small intestinal histological lesion of coeliac disease was found, and this diagnosi...
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An improved technique for the detection of alpha-gliadin sensitised mononuclear cells in the peripheral blood of untreated coeliac patients is described. This method is a modification of the direct LMIF assay, and involves exposure of lymphocytes to alpha-gliadin and the assay of the resultant lymphokine produced using normal leucocytes as indicator cells. All untreated coeliac patients, 14 of ...
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The relationship between wheat flour in the diet and the development of symptoms in children with coeliac disease observed by Dicke (1950) has been established. Subsequent investigations indicated that the injurious factor occurs principally in the gliadin ifraction (van de Kamer, Weijers and Dicke, 1953). Weijers and van de Kamer (1955) used gliadin in a method of testing wheat sensitivity hop...
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Ose, L., and Fluge, G. (1974). The D-xylose tolerance test as screening test for malabsorption disorders in infancy and and childhood. Tidsskrift for Den Norske Legeforening, 94, 1192. Rolles, C. J., Anderson, C. M., and McNeish, A. S. (1975). Confirming persistence of gluten intolerance in children diagnosed as having coeliac disease in infancy: usefulness of one-hour blood xylose test. Archiv...
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ژورنال
عنوان ژورنال: BMJ
سال: 1983
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.286.6383.2007